1. Make the Key Lime Curd:
- Combine the granulated sugar, Key lime juice, egg, and egg yolk in a small saucepan over medium-low heat.
- Whisk until the sugar dissolves, about 1 minute.
- Whisking constantly, add the cold butter, a few pieces at a time, waiting until it melts before adding more.
- Continue whisking until the curd is thick and coats the back of a spoon, 3 to 4 minutes.
- Transfer the curd to a small bowl and refrigerate until chilled, about 1 hour.
2. Make the Cupcakes:
- Preheat the oven to 350°F (175°C).
- Line 24 muffin cups with paper liners.
- Prepare the cake mix according to the package directions for cupcakes.
- Bake and cool as directed on the box.
3. Make the Frosting:
- Beat the softened butter, softened cream cheese, and Key lime juice in a large bowl with a mixer on medium-high speed until light and fluffy, 3 to 4 minutes.
- Reduce the speed to low and slowly add the powdered sugar.
- Continue to beat until just combined, 1 to 2 minutes. Be careful not to overbeat.
4. Assemble the Cupcakes:
- Use a paring knife to cut a small hole in the top of each cooled cupcake, about 1/2 inch deep and 1/2 inch in diameter.
- Spoon 1/2 teaspoon of the chilled Key lime curd into each hole.
- Spread the frosting on the cupcakes.
- Sprinkle with graham cracker crumbs.
- Top each cupcake with a thin lime slice.